Papers and publications

EDP-938 : RSV inhibitor as a potential treatment intervention?

Alaa Ahmad, Ph.D., Kingsley Eze, B.Sc., Nicolas Noulin, Ph.D., Veronika Horvathova, M.B., Ch.B., Bryan Murray, M.B., B.S., Mark Baillet, B.Sc., C.Stat., Laura Grey, Ph.D., Julie Mori, Ph.D., and Nathalie Adda

Adda et al. investigated a potential inhibitor of respiratory syncytial virus (RSV) in a human challenge study. An inhibitor, known as EDP-938, would act in such a way whereby it would alter and interfere with a protein that allows for RSV to replicate in the human...

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The drivers of the RSV rebound during the COVID-19 pandemic.

You Li, PhD, Xin Wang, PhD, Bingbing Cong, BMed, Shuyu Deng, BMed, Daniel R Feikin, MD, Harish Nair, PhDYou Li and co-workers investigated why RSV has rebounded after the expected local RSV season in several countries during the COVID-19 pandemic. The RSV epidemic was late in the 18 countries included, and 11 observed a rebound before September 2021. The risk of observing a rebound of RSV was 23 times higher after re-opening schools. On the contrary, an increase in temperature of 5°C decreas […]

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Increasing RSV PICU admissions after large-scale introduction of high flow nasal cannula

Linssen RS, Bem RA, Kapitein B, Rengerink KO, Otten MH, den Hollander B, Bont L, van Woensel JBMHigh flow oxygen intends to decrease work of breathing and prevent respiratory failure. Despite trials have shown benefit, high flow oxygen has not brought the success hoped for as it did not decrease the need for PICU admissions. This study studied trends in 15,606 pediatric intensive care unit (PICU) admissions for (RSV) bronchiolitis in The Netherlands, France, Scotland, Belgium, Italy and Norway b […]

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